ICEMAN Assessment Tool

Interactive forms for RCTs and meta-analyses — Version 1.1

Interactive ICEMAN version 1.1 forms for assessing the credibility of apparent effect modification in randomized trials and meta-analyses.

Study type

Preliminary considerations

Outcome and time-point

Effect measure

Effect modifier

Does the analysis suggest a possible effect modification (interaction p < 0.1)?

Select… Yes No, stop here

Note: ICEMAN was developed to assess the credibility of a suggested effect modification (interaction p < 0.1). It does not apply when there is no suggestion of effect modification. Assessing the credibility of an absence of effect modification requires a different approach not covered by ICEMAN. See manual for scope of ICEMAN →

Summary of responses

— Fill in the items above to see a summary —

Overall rating

How would you rate the overall credibility of the proposed effect modification?

Click scale to rate manually

Very lowLowModerateHigh

Preliminary considerations

Outcome and time-point

Effect measure

Effect modifier

Does the analysis suggest a possible effect modification (interaction p < 0.1)?

Select… Yes No, stop here

Note: ICEMAN was developed to assess the credibility of a suggested effect modification (interaction or meta-regression p < 0.1). It does not apply when there is no suggestion of effect modification. Assessing the credibility of an absence of effect modification requires a different approach not covered by ICEMAN. See manual for scope of ICEMAN →

Summary of responses

— Fill in the items above to see a summary —

Overall rating

How would you rate the overall credibility?

Click scale to rate manually

Very lowLowModerateHigh

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