Additional information
Publications
Main article:
Stefan Schandelmaier, Matthias Briel, Ravi Varadhan, Christopher Schmid, Phd, Niveditha Devasenapathy, Rodney Hayward, Md, Joel j Gagnier, Michael Borenstein, Geert JMG VanDerHeijden, Issa J Dahabreh, Xin Sun, Willi Sauerbrei, Michael Walsh, John Ioannidis, Lehana Thabane, Gordon Guyatt. 2020. A New Instrument to Assess the Credibility of Effect Modification Analyses (ICEMAN) in Randomized Controlled Trials and Meta-Analyses. CMAJ. 2020 192(32):E901-E906
Using ICEMAN together with GRADE:
Guyatt G, Zhao Y, Mayer M, Briel M, Mustafa R, Izcovich A, Hultcrantz M, Iorio A, Alba AC, Foroutan F, Sun X, Schunemann H, DeBeer H, Akl EA, Christensen R, Schandelmaier S. GRADE guidance 36: updates to GRADE’s approach to addressing inconsistency. J Clin Epidemiol. 2023 Jun;158:70–83.
A commentary on meta-research using ICEMAN criteria:
Schandelmaier S, Guyatt G. Same Old Challenges in Subgroup Analysis-Should We Do More About Methods Implementation? JAMA Netw Open. 2024 Mar 4;7(3):e243339.
The PATH statement that endorses ICEMAN:
Kent DM, Paulus JK, van Klaveren D, D'Agostino R, Goodman S, Hayward R, Ioannidis JPA, Patrick-Lake B, Morton S, Pencina M, Raman G, Ross JS, Selker HP, Varadhan R, Vickers A, Wong JB, Steyerberg EW. The Predictive Approaches to Treatment effect Heterogeneity (PATH) Statement. Ann Intern Med. 2020 Jan 7;172(1):35-45.
A related systematic survey of previous credibility criteria:
Schandelmaier S, Chang Y, Malgorzata B, Devasenapathy N, Devji T, Kwong JSW, Colunga Lozano LE, Lee Y, Agarwal A, Bhatnagar N, Ewald H, Zhang Y, Sun X, Thabane L, Walsh M, Briel M, Guyatt GH. A systematic survey identified 36 criteria for assessing effect modification claims in randomized trials or meta-analyses. J Clin Epidemiol. 2019 Sep;113:159-167.
Related doctoral thesis:
Schandelmaier, Stefan. 2019. Evaluating the Credibility of Effect Modification Claims in Randomized Controlled Trials and Meta-Analyses. PhD. Doctoral Thesis Published on Macsphere.
Funding: The Swiss National Science foundation, the Gottfried and Julia Bangerter-Rhyner-Foundation, and the Freiwillige Akademische Gesellschaft Basel supported the development of ICEMAN through personal grants to Stefan Schandelmaier.